Assay Detail
Functional
CHEMBL666033
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Compound was tested for antiviral activity against human cytomegalovirus (HCMV) plaque reduction assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Benzimidazole ribonucleosides: Observation of an unexpected nitration when performing non-aqueous diazotizations with t-butyl nitrite
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.60 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 5.10 |
| CHEMBL605800 | — | — | 1 | 4.52 |
| CHEMBL603513 | — | — | 1 | 4.40 |
| CHEMBL375530 | DICHLORORIBOBENZIMIDAZOLE | — | 1 | 4.38 |
| CHEMBL608658 | — | — | 1 | - |
| CHEMBL605799 | — | — | 1 | - |
| CHEMBL608318 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL605800 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL603513 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL375530 | DICHLORORIBOBENZIMIDAZOLE | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL608658 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL605799 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL608318 | — | IC50 | > | 100000.0 | nM | - |