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Assay Detail

CHEMBL666765

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for inhibition activity against factor Xa (FXa)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Coagulation factor X (CHEMBL244)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xa inhibitors.
Phillips G, Davey DD, Eagen KA, Koovakkat SK, Liang A, Ng HP, Pinkerton M, Trinh L, Whitlow M, Beatty AM, Morrissey MM.
J Med Chem (1999) 42 : 1749 -1756
PubMed 10346927 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.66 7.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL19902 DX-9065A 1 7.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL19902 DX-9065A Ki = 22.0 nM 7.66