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Assay Detail

CHEMBL666786

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antagonistic activity against cholecystokinin type B receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Gastrin/cholecystokinin type B receptor (CHEMBL298)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Excursions in drug discovery.
Patchett AA.
J Med Chem (1993) 36 : 2051 -2058
PubMed 8340909 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.90 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL9387 L-365260 1 8.70
CHEMBL37312 1 7.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL9387 L-365260 IC50 = 2.0 nM 8.70
CHEMBL37312 IC50 = 81.0 nM 7.09