Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL667907

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (21-37).
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Dopamine beta-hydroxylase (CHEMBL4702)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Multisubstrate inhibitors of dopamine beta-hydroxylase. 2. Structure-activity relationships at the phenethylamine binding site.
Kruse LI, Kaiser C, DeWolf WE, Frazee JS, Ross ST, Wawro J, Wise M, Flaim KE, Sawyer JL, Erickson RW.
J Med Chem (1987) 30 : 486 -494
PubMed 3820219 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.55 4.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL65495 1 4.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL65495 IC50 = 28000.0 nM 4.55