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Assay Detail

CHEMBL668655

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(1A) dopamine receptor (CHEMBL3071)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Conformational analysis and structure-activity relationships of selective dopamine D-1 receptor agonists and antagonists of the benzazepine series.
Pettersson I, Liljefors T, Bøgesø K.
J Med Chem (1990) 33 : 2197 -2204
PubMed 1973733 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.40 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL62 SCH-23390 1 9.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL62 SCH-23390 Ki = 0.4 nM 9.40