Assay Detail
Binding
CHEMBL671785
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In vitro binding activity against dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligand.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Resolved 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8-amine: central dopamine and serotonin receptor stimulating properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.65 | 4.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL413105 | — | — | 1 | 4.71 |
| CHEMBL303339 | — | — | 1 | 4.69 |
| CHEMBL292274 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL413105 | — | IC50 | = | 19700.0 | nM | 4.71 |
| CHEMBL303339 | — | IC50 | = | 20400.0 | nM | 4.69 |
| CHEMBL292274 | — | IC50 | = | 29200.0 | nM | 4.54 |