Assay Detail
Binding
CHEMBL671951
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Inhibition of binding of [3H]SCH-23390 to Dopamine receptor D1 in rat striatal membranes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Cis- and trans-N-benzyl-octahydrobenzo[g]quinolines. Adrenergic and dopaminergic activity studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.21 | 6.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | 4.0 | 1 | 6.37 |
| CHEMBL170475 | — | — | 1 | 6.35 |
| CHEMBL170974 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53 | APOMORPHINE | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL170475 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL170974 | — | IC50 | = | 1200.0 | nM | 5.92 |