Assay Detail

CHEMBL671985

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Functional

Inhibitory concentration against growth of cultured duadi cells at 144 hrs.

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Open DB target context

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Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Synthetic polyamine analogues as antineoplastics.

Bergeron RJ, Neims AH, McManis JS, Hawthorne TR, Vinson JR, Bortell R, Ingeno MJ.
J Med Chem (1988) 31 : 1183 -1190
PubMed 3373487 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.30	6.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL18794	BIS(ETHYL)SPERMINE	—	1	6.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL18794	BIS(ETHYL)SPERMINE	IC50	=	500.0	nM	6.30