Assay Detail
Binding
CHEMBL672001
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Ability to displace [3H]SCH-23390 binding to rat striatal Dopamine receptor D1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(R)-11-hydroxy- and (R)-11-hydroxy-10-methylaporphine: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.91 | 7.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL119455 | — | — | 1 | 7.69 |
| CHEMBL53 | APOMORPHINE | 4.0 | 1 | 6.63 |
| CHEMBL53510 | — | — | 1 | 6.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL119455 | — | Ki | = | 20.4 | nM | 7.69 |
| CHEMBL53 | APOMORPHINE | Ki | = | 236.0 | nM | 6.63 |
| CHEMBL53510 | — | Ki | = | 382.0 | nM | 6.42 |