Assay Detail
Binding
CHEMBL672009
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Binding affinity against Dopamine receptor D1 from rat brain corpus striatal preparations using [3H]SCH-23390
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and dopamine agonist and antagonist effects of (R)-(-)- and (S)-(+)-11-hydroxy-N-n-propylnoraporphine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.14 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31973 | — | — | 1 | 6.47 |
| CHEMBL27559 | — | — | 1 | 6.36 |
| CHEMBL27574 | — | — | 1 | 5.87 |
| CHEMBL283489 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31973 | — | Ki | = | 340.0 | nM | 6.47 |
| CHEMBL27559 | — | Ki | = | 434.0 | nM | 6.36 |
| CHEMBL27574 | — | Ki | = | 1345.0 | nM | 5.87 |
| CHEMBL283489 | — | Ki | = | 1413.0 | nM | 5.85 |