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Assay Detail

CHEMBL672682

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for its affinity towards Dopamine receptor D1 in rat striatal membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Striatum
Subcellular Membrane
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(1A) dopamine receptor (CHEMBL265)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Dopaminergic benzo[a]phenanthridines: resolution and pharmacological evaluation of the enantiomers of dihydrexidine, the full efficacy D1 dopamine receptor agonist.
Knoerzer TA, Nichols DE, Brewster WK, Watts VJ, Mottola D, Mailman RB.
J Med Chem (1994) 37 : 2453 -2460
PubMed 7914538 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL24077 (R)-SKF-38393 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL24077 (R)-SKF-38393 EC50 = 100.0 nM 7.00