Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL672933

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Evaluated for the inhibition of binding of [3H]DA (dopamine) to dopamine receptor in calf striatal homogenate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Dopamine receptor (CHEMBL2096970)
Type PROTEIN FAMILY
Organism Bos taurus

Publication

Synthesis and dopamine receptor binding of exo- and endo-2-amino-6,7-dihydroxybenzonorbornene, rigid analogues of 2-amino-6,7-dihydroxytetrahydronaphthalene.
Schuster DI, Katerinopoulos HE, Holden WL, Narula AP, Libes RB, Murphy RB.
J Med Chem (1982) 25 : 850 -854
PubMed 7108901 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.22 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL26736 1 8.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL26736 IC50 = 6.0 nM 8.22