Dopamine receptor · PROTEIN FAMILY · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt Q95136. Use UniProt Q95136 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q95136 as the stable identity anchor, then attach disease evidence before program review.
D(1A) dopamine receptor
Review this target as Dopamine receptor, mapped to UniProt Q95136. ChEMBL maps the protein component as D(1A) dopamine receptor. Sequence length is 446 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dopamine receptor as ChEMBL target CHEMBL2096970, mapped to UniProt Q95136. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dopamine receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Bos taurus |
| UniProt | Q95136 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | D(1A) dopamine receptor |
| UniProt Accession | Q95136 |
| Component Type | Protein |
| Sequence Length | 446 aa |
D(1A) dopamine receptor
Review this target as Dopamine receptor, mapped to UniProt Q95136. ChEMBL maps the protein component as D(1A) dopamine receptor. Sequence length is 446 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL53 | 9.0 | IC50 | 1.0 | Approved |
| CHEMBL288096 | 8.94 | Ki | 1.15 | Preclinical |
| CHEMBL225230 | 8.82 | Ki | 1.5 | Preclinical |
| CHEMBL54 | 8.74 | IC50 | 1.8 | Approved |
| CHEMBL148829 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL19130 | 8.66 | Ki | 2.18 | Preclinical |
| CHEMBL1237207 | 8.46 | IC50 | 3.5 | Preclinical |
| CHEMBL53 | 8.43 | Ki | 3.7 | Approved |
| CHEMBL59 | 8.43 | IC50 | 3.7 | Approved |
| CHEMBL53294 | 8.42 | Ki | 3.84 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 22 | 33 | 6.6 |
| assay format | 18 | 10 | 7.5 |
| tissue-based format | 4 | 14 | 4.9 |
| cell membrane format | 1 | 8 | 6.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 9 | 7.9 |