Compound Detail
CHEMBL1237207
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CCCN1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c1-3.CCCN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3
Basic Information
| ChEMBL ID | CHEMBL1237207 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DYWPVIPTSOGLMW-ZWZQDMJTSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
590.8
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 8.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dopamine receptor CHEMBL2096970 | IC50 | 8.46 | 7.6433 | 3.5 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dopamine receptor | IC50 | = | 3.5 | nM | 8.46 | Binding affinity against dopamine receptor from P4 fractions of caudate nucleus ... | 6682147 |
| Dopamine receptor | IC50 | = | 5.0 | nM | 8.3 | Binding affinity against dopamine receptor from P4 fractions of caudate nucleus ... | 6682147 |
| Dopamine receptor | IC50 | = | 670.0 | nM | 6.17 | Binding affinity against dopamine receptor from P4 fractions of caudate nucleus ... | 6682147 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6682147 | 10.1021/jm00358a011 | Dopamine receptor | 3 |
| 6682147 | 10.1021/jm00358a011 | Rattus norvegicus | 2 |
Data from ChEMBL 36 via Core Engine