Assay Detail
Binding
CHEMBL670111
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Binding affinity against dopamine receptor from P4 fractions of caudate nucleus (calf brain), using [3H]ADTN as the radioligand at a concentration of 0.5 nM
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Aporphines. 48. Enantioselectivity of (R)-(-)- and (S)-(+)-N-n-propylnorapomorphine on dopamine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.13 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL148829 | — | — | 1 | 8.70 |
| CHEMBL1237207 | — | — | 1 | 8.46 |
| CHEMBL356035 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL148829 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL1237207 | — | IC50 | = | 3.5 | nM | 8.46 |
| CHEMBL356035 | — | IC50 | = | 60.0 | nM | 7.22 |