Assay Detail
Binding
CHEMBL672939
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In vitro inhibitory activity was evaluated against,[3H]dopamine (DA),calf caudate dopamine receptor
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Resolution and absolute configuration of the potent dopamine agonist N,N-diethyl-N'-[(3 alpha, 4a alpha, 10a beta)-1,2,3,4,4a,5,10,10a- -octahydro-6-hydroxy-1-propyl-3-benzo[g]quinolinyl]sulfamide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.92 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2218861 | QUINAGOLIDE | 4.0 | 2 | 7.12 |
| CHEMBL38992 | ETISULERGINE | 2.0 | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2218861 | QUINAGOLIDE | IC50 | = | 75.0 | nM | 7.12 |
| CHEMBL38992 | ETISULERGINE | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL2218861 | QUINAGOLIDE | IC50 | = | 190.0 | nM | 6.72 |