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Assay Detail

CHEMBL672962

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for the competitive binding with [3H]spiperone binding to Canine striatal membranes.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Canis lupus familiaris
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Dopamine receptor (CHEMBL2096905)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Aporphines. 58. N-(2-chloroethyl) [8,9-2H]norapomorphine, an irreversible ligand for dopamine receptors: synthesis and application.
Guan JH, Neumeyer JL, Filer CN, Ahern DG, Lilly L, Watanabe M, Grigoriadis D, Seeman P.
J Med Chem (1984) 27 : 806 -810
PubMed 6737423 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.10 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL283871 1 5.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL283871 IC50 = 8000.0 nM 5.10