Assay Detail
Binding
CHEMBL673835
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Binding affinity against Dopamine receptor D3
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Selective optimization of side activities: another way for drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.82 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL286252 | NAFADOTRIDE | — | 1 | 9.96 |
| CHEMBL428705 | — | — | 1 | 7.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL286252 | NAFADOTRIDE | Ki | = | 0.11 | nM | 9.96 |
| CHEMBL428705 | — | Ki | = | 21.0 | nM | 7.68 |