Assay Detail

CHEMBL673900

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Functional

Compound was tested for antiproliferative effect against primary endothelial cells from pork aorta(ECPA) at concentration of 0.001 uM

ChEMBL ↗

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Target

ADMET (CHEMBL612558) ↗

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Primary target ADMET

CHEMBL612558

Anchored from Assay target.

Protein identity ADMET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Sus scrofa
Cell Type	Endothelial cell
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

ADMET (CHEMBL612558) ↗

Type

ADMET

Publication

Synthesis and antiangiogenic activity of new carbohydrate derivatives

Dorey G, Leon P, Sciberras S, Leonce S, Guilbaud N, Pierre A, Atassi G, Billington D
Bioorg Med Chem Lett (1996) 6 : 3045 -3050
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.92	4.92

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL424278	O-CHLOROACETYLCARBAMOYLFUMAGILLOL	2.0	1	4.92

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL424278	O-CHLOROACETYLCARBAMOYLFUMAGILLOL	IC50	=	12000.0	nM	4.92