Assay Detail
Functional
CHEMBL674527
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for its inhibitory activity against U 46619-induced contraction of saphenous vein in dog.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Canis lupus familiaris |
| Tissue | Saphenous vein |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 3. Pyridinylalkyl-substituted 8-[(arylsulfonyl)amino]octanoic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 8.53 | 8.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65414 | — | — | 1 | 8.90 |
| CHEMBL136845 | — | — | 1 | 8.76 |
| CHEMBL337331 | — | — | 1 | 7.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65414 | — | Kd | = | 1.259 | nM | 8.90 |
| CHEMBL136845 | — | Kd | = | 1.738 | nM | 8.76 |
| CHEMBL337331 | — | Kd | = | 11.75 | nM | 7.93 |