Assay Detail
Binding
CHEMBL674699
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Inhibition of Epidermal growth factor receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Structural influences of styryl-based inhibitors on epidermal growth factor receptor and p56lck tyrosine-specific protein kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.27 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL47986 | ERBSTATIN | — | 1 | 5.52 |
| CHEMBL296407 | — | — | 1 | 5.40 |
| CHEMBL46946 | — | — | 1 | 5.16 |
| CHEMBL47660 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL47986 | ERBSTATIN | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL296407 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL46946 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL47660 | — | IC50 | = | 10000.0 | nM | 5.00 |