Assay Detail
Binding
CHEMBL675203
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Irreversible inhibition of [3H]estradiol binding to lamb uterine estrogen receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Ovis aries |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Intermediate |
Publication
Steroidal affinity labels of the estrogen receptor. 2. 17 alpha-[(Haloacetamido)alkyl]estradiols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.46 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1628077 | — | — | 1 | 7.75 |
| CHEMBL1627886 | — | — | 1 | 7.28 |
| CHEMBL1627885 | — | — | 1 | 5.80 |
| CHEMBL1628080 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1628077 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL1627886 | — | IC50 | = | 53.0 | nM | 7.28 |
| CHEMBL1627885 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL1628080 | — | IC50 | = | 9700.0 | nM | 5.01 |