Assay Detail
Functional
CHEMBL675877
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Effect of compound on synaptosomal uptake inhibition of Dopamine (DA)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Neuroleptic activity and dopamine-uptake inhibition in 1-piperazino-3-phenylindans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.00 | 8.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL322067 | — | — | 1 | 8.03 |
| CHEMBL173861 | — | — | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL322067 | — | IC50 | = | 9.3 | nM | 8.03 |
| CHEMBL173861 | — | IC50 | = | 11.0 | nM | 7.96 |