Assay Detail
Binding
CHEMBL676549
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Compound was evaluated for the binding affinity to Endothelin B receptor in the rat cerebellum
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Cerebellum |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Endothelin: a new challenge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 10.80 | 10.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4524099 | — | — | 1 | 10.89 |
| CHEMBL437472 | ENDOTHELIN | 2.0 | 1 | 10.82 |
| CHEMBL4524100 | — | — | 1 | 10.80 |
| CHEMBL1790180 | ENDOTHELIN 3 | 0.5 | 1 | 10.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4524099 | — | Ki | = | 0.013 | nM | 10.89 |
| CHEMBL437472 | ENDOTHELIN | Ki | = | 0.015 | nM | 10.82 |
| CHEMBL4524100 | — | Ki | = | 0.016 | nM | 10.80 |
| CHEMBL1790180 | ENDOTHELIN 3 | Ki | = | 0.021 | nM | 10.68 |