Assay Detail
Binding
CHEMBL677047
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In vitro binding affinity for estrogen receptor beta
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
A novel estrogen receptor ligand template.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.06 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL135 | ESTRADIOL | 4.0 | 1 | 8.70 |
| CHEMBL57150 | — | — | 1 | 7.12 |
| CHEMBL81 | RALOXIFENE | 4.0 | 1 | 6.33 |
| CHEMBL294889 | — | — | 1 | 6.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL135 | ESTRADIOL | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL57150 | — | IC50 | = | 75.0 | nM | 7.12 |
| CHEMBL81 | RALOXIFENE | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL294889 | — | IC50 | = | 850.0 | nM | 6.07 |