Assay Detail
Binding
CHEMBL677084
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Inhibitory activity against fucosyltransferase (FucT V) in the presence of fucosyl acceptor N-acetyllactosamine
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (CHEMBL3146) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of fucosyltransferase V by a GDP-Azasugar.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.17 | 4.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL384759 | — | — | 1 | 4.17 |
| CHEMBL1160214 | — | — | 1 | - |
| CHEMBL53188 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL384759 | — | IC50 | = | 67000.0 | nM | 4.17 |
| CHEMBL1160214 | — | IC50 | > | 500000.0 | nM | - |
| CHEMBL53188 | — | IC50 | > | 1000000.0 | nM | - |