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Assay Detail

CHEMBL677591

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Functional
Agonistic activity in CHO-hFollicle stimulating hormone receptor cell-based cAMP accumulation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Follicle-stimulating hormone receptor (CHEMBL2024)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis.
Guo T, Adang AE, Dong G, Fitzpatrick D, Geng P, Ho KK, Jibilian CH, Kultgen SG, Liu R, McDonald E, Saionz KW, Valenzano KJ, van Straten NC, Xie D, Webb ML.
Bioorg Med Chem Lett (2004) 14 : 1717 -1720
PubMed 15026057 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.50 7.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL279759 1 7.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL279759 EC50 = 32.0 nM 7.50