Assay Detail
Binding
CHEMBL677809
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In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystol
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Synthesis and estrogen receptor selectivity of 1,1-bis(4-hydroxyphenyl)-2-(p-halophenyl)ethylenes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 8.35 | 8.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285536 | — | — | 1 | 8.54 |
| CHEMBL415864 | — | — | 1 | 8.49 |
| CHEMBL287352 | — | — | 1 | 8.48 |
| CHEMBL34648 | — | — | 1 | 8.35 |
| CHEMBL135 | ESTRADIOL | 4.0 | 1 | 8.24 |
| CHEMBL33879 | — | — | 1 | 7.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285536 | — | EC50 | = | 2.9 | nM | 8.54 |
| CHEMBL415864 | — | EC50 | = | 3.2 | nM | 8.49 |
| CHEMBL287352 | — | EC50 | = | 3.3 | nM | 8.48 |
| CHEMBL34648 | — | EC50 | = | 4.5 | nM | 8.35 |
| CHEMBL135 | ESTRADIOL | EC50 | = | 5.7 | nM | 8.24 |
| CHEMBL33879 | — | EC50 | = | 10.4 | nM | 7.98 |