Assay Detail
Binding
CHEMBL677816
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Binding affinity for rat estrogen receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Bone targeted drugs 2. synthesis of estrogens with hydroxyapatite affinity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.73 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL9225 | HEXESTROL | 4.0 | 1 | 8.70 |
| CHEMBL266377 | — | — | 1 | 5.30 |
| CHEMBL267891 | — | — | 1 | 4.92 |
| CHEMBL9428 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL9225 | HEXESTROL | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL266377 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL267891 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL9428 | — | IC50 | = | 100000.0 | nM | 4.00 |