Assay Detail
Binding
CHEMBL677819
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Equilibrium dissociation constant for rat uterine estrogen receptor binding [3H]estradiol
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Steroids. 2. Synthesis of C-18 functionalized steroids via the Smith-Hughes route.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 7.39 | 9.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1627822 | — | — | 1 | 9.21 |
| CHEMBL1162 | NORETHINDRONE | 4.0 | 1 | 9.20 |
| CHEMBL103 | PROGESTERONE | 4.0 | 1 | 8.41 |
| CHEMBL1794824 | — | — | 1 | 6.80 |
| CHEMBL15128 | — | — | 1 | 6.66 |
| CHEMBL14506 | — | — | 1 | 6.14 |
| CHEMBL273571 | — | — | 1 | 5.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1627822 | — | Kd | = | 0.62 | nM | 9.21 |
| CHEMBL1162 | NORETHINDRONE | Kd | = | 0.63 | nM | 9.20 |
| CHEMBL103 | PROGESTERONE | Kd | = | 3.9 | nM | 8.41 |
| CHEMBL1794824 | — | Kd | = | 160.0 | nM | 6.80 |
| CHEMBL15128 | — | Kd | = | 220.0 | nM | 6.66 |
| CHEMBL14506 | — | Kd | = | 730.0 | nM | 6.14 |
| CHEMBL273571 | — | Kd | = | 5100.0 | nM | 5.29 |