Assay Detail
Binding
CHEMBL677879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of epidermal growth factor receptor (EGF-R)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
7-Pyrrolidinyl- and 7-piperidinyl-5-aryl-pyrrolo[2,3-d]pyrimidines--potent inhibitors of the tyrosine kinase c-Src.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.27 | 6.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL172514 | — | — | 1 | 6.51 |
| CHEMBL274732 | — | — | 1 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL172514 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL274732 | — | IC50 | = | 930.0 | nM | 6.03 |