Assay Detail
Functional
CHEMBL678166
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Concentration required to reduce herpes simplex virus-1TK( B2006) inducted cytopathicity by 50% (E6SM cells)
9
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | E6SM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Polyanion inhibitors of human immunodeficiency virus and other viruses. 6. Micelle-like anti-HIV polyanionic compounds based on a carbohydrate core.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.26 | 4.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3215377 | — | — | 1 | 4.35 |
| CHEMBL3217279 | — | — | 1 | 4.17 |
| CHEMBL3142960 | — | — | 1 | - |
| CHEMBL3142956 | — | — | 1 | - |
| CHEMBL384019 | — | — | 2 | - |
| CHEMBL3215376 | — | — | 1 | - |
| CHEMBL3142950 | — | — | 1 | - |
| CHEMBL3215375 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3215377 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL3217279 | — | IC50 | = | 68000.0 | nM | 4.17 |
| CHEMBL3142960 | — | IC50 | > | 237000.0 | nM | - |
| CHEMBL3142956 | — | IC50 | > | 203000.0 | nM | - |
| CHEMBL384019 | — | IC50 | > | 181000.0 | nM | - |
| CHEMBL3215376 | — | IC50 | > | 333000.0 | nM | - |
| CHEMBL384019 | — | IC50 | > | 181000.0 | nM | - |
| CHEMBL3142950 | — | IC50 | > | 181000.0 | nM | - |
| CHEMBL3215375 | — | IC50 | > | 296000.0 | nM | - |