Assay Detail
Functional
CHEMBL678238
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CHO-L6 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.68 | 9.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301265 | PRAMIPEXOLE | 4.0 | 1 | 9.68 |
| CHEMBL116372 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301265 | PRAMIPEXOLE | EC50 | = | 0.21 | nM | 9.68 |
| CHEMBL116372 | — | EC50 | > | 1000.0 | nM | - |