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Assay Detail

CHEMBL678365

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for inhibition of Ent. cloacae 908R in combination with Ceftriaxone
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterobacter cloacae
Confidence 1 — Organism
Curated By Intermediate

Target

Enterobacter cloacae (CHEMBL349)
Type ORGANISM
Organism Enterobacter cloacae

Publication

Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases.
Richter HG, Angehrn P, Hubschwerlen C, Kania M, Page MG, Specklin JL, Winkler FK.
J Med Chem (1996) 39 : 3712 -3722
PubMed 8809160 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.10 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL123029 1 5.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL123029 IC50 = 8000.0 nM 5.10