Assay Detail
Functional
CHEMBL678367
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Tested in vitro for the beta lactamase inhibition of Enterobacter cloacae
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterobacter cloacae |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antibacterial activity of (1R, 5R, 6R)-2-tert-butyl-6-(1-hydroxyethyl)penem-3-carboxylic acid
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.41 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL304733 | — | — | 1 | 8.70 |
| CHEMBL69141 | — | — | 1 | 6.52 |
| CHEMBL777 | CLAVULANIC ACID | 4.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL304733 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL69141 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL777 | CLAVULANIC ACID | IC50 | = | 100000.0 | nM | 4.00 |