Assay Detail
Binding
CHEMBL678646
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The Dissociation Constant for Gamma-amino-N-butyrate transaminase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
4-aminobutyrate aminotransferase, mitochondrial (CHEMBL2266) ↗| Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
Publication
Slow-binding inhibition of gamma-aminobutyric acid aminotransferase by hydrazine analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.95 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL352205 | 3-HYDROXYBENZYLHYDRAZINE DIHYDROCHLORIDE | — | 1 | 6.34 |
| CHEMBL160520 | METHYLHYDRAZINE | — | 1 | 5.55 |
| CHEMBL159205 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL352205 | 3-HYDROXYBENZYLHYDRAZINE DIHYDROCHLORIDE | Kd | = | 460.0 | nM | 6.34 |
| CHEMBL160520 | METHYLHYDRAZINE | Kd | = | 2800.0 | nM | 5.55 |
| CHEMBL159205 | — | Kd | < | 20.0 | nM | - |