Compound Detail
CHEMBL160520
METHYLHYDRAZINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL160520 |
| Name | METHYLHYDRAZINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HDZGCSFEDULWCS-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
46.1
MW (Da)
-0.92
ALogP
2
HBA
2
HBD
38.0
PSA (Ų)
0.27
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.55
Ki 1 meas. best 5.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 4-aminobutyrate aminotransferase, mitochondrial CHEMBL2266 | Ki | 5.66 | 5.66 | 2200.0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial CHEMBL2266 | Kd | 5.55 | 5.55 | 2800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 4-aminobutyrate aminotransferase, mitochondrial | Ki | = | 2200.0 | nM | 5.66 | Inhibitory activity against Gamma-amino-N-butyrate transaminase | 8576911 |
| 4-aminobutyrate aminotransferase, mitochondrial | Kd | = | 2800.0 | nM | 5.55 | The Dissociation Constant for Gamma-amino-N-butyrate transaminase | 8576911 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8576911 | 10.1021/jm950437v | 4-aminobutyrate aminotransferase, mitochondrial | 5 |
Data from ChEMBL 36 via Core Engine