Assay Detail
Binding
CHEMBL679597
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for Farnesyl Transferase Inhibition to displace 50% of radiolabeled Farnesyltransferase inhibitors from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells using Cell-based Radiotracer Assay (CRAFT1)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Rat1 |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Potent inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.24 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23217 | — | — | 1 | 6.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23217 | — | IC50 | = | 576.0 | nM | 6.24 |