Assay Detail
Functional
CHEMBL679667
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Partial agonist activity against human rho-1 subunit GABA-C receptor expressed in Xenopus oocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Oocyte |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Gamma-aminobutyric acid receptor subunit rho-1 (CHEMBL3561) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.36 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33086 | t-4-AMINOCROTONIC ACID (TACA) | — | 1 | 6.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33086 | t-4-AMINOCROTONIC ACID (TACA) | EC50 | = | 440.0 | nM | 6.36 |