Assay Detail
Binding
CHEMBL680441
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of bovine farnesyl transferase
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Local constrained shifty pseudopeptides inhibitors of rasfarnesyl transferase
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.45 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL91722 | — | — | 1 | 7.68 |
| CHEMBL327674 | — | — | 1 | 7.64 |
| CHEMBL289302 | — | — | 2 | 7.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL91722 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL327674 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL289302 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL289302 | — | IC50 | = | 60.0 | nM | 7.22 |