Assay Detail
Functional
CHEMBL680543
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In vitro antiviral activity against Epstein Barr virus (EBV) was determined
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human gammaherpesvirus 4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5-Bromo (or chloro)-6-azido-5,6-dihydro-2' -deoxyuridine and -thymidine derivatives with potent antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 4.89 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 5.40 |
| CHEMBL3142666 | — | — | 1 | 5.01 |
| CHEMBL3142658 | — | — | 1 | 4.80 |
| CHEMBL3142668 | — | — | 1 | 4.34 |
| CHEMBL3142665 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | EC50 | = | 3960.0 | nM | 5.40 |
| CHEMBL3142666 | — | EC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL3142658 | — | EC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL3142668 | — | EC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL3142665 | — | EC50 | > | 12500.0 | nM | - |