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Assay Detail

CHEMBL680570

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration against glycogen phosphorylase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glycogen phosphorylase, liver form (CHEMBL3008)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Fragment-based drug discovery.
Erlanson DA, McDowell RS, O'Brien T.
J Med Chem (2004) 47 : 3463 -3482
PubMed 15214773 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.67 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL434025 1 8.22
CHEMBL319136 1 6.89
CHEMBL325455 1 4.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL434025 IC50 = 6.0 nM 8.22
CHEMBL319136 IC50 = 130.0 nM 6.89
CHEMBL325455 IC50 = 12500.0 nM 4.90