Compound Detail
CHEMBL434025
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Basic Information
| ChEMBL ID | CHEMBL434025 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MWWXABBBAPKJDX-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
503.4
MW (Da)
4.15
ALogP
4
HBA
4
HBD
108.2
PSA (Ų)
0.23
QED
1
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen phosphorylase, liver form CHEMBL2568 | IC50 | 8.22 | 8.22 | 6.0 | 1 |
| Glycogen phosphorylase, liver form CHEMBL3008 | IC50 | 8.22 | 8.22 | 6.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen phosphorylase, liver form | IC50 | = | 6.0 | nM | 8.22 | Inhibitory concentration against glycogen phosphorylase | 15214773 |
| Glycogen phosphorylase, liver form | IC50 | = | 6.0 | nM | 8.22 | Inhibition of glycogen phosphorylase a (unknown origin) | 25092521 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15214773 | 10.1021/jm040031v | Glycogen phosphorylase, liver form | 1 |
| 25092521 | 10.1016/j.bmc.2014.06.058 | Glycogen phosphorylase, liver form | 1 |
Data from ChEMBL 36 via Core Engine