Assay Detail
Binding
CHEMBL680747
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Selectivity for gardos channel; (Gardos channel vs 2000 nM for the cardiac IKs channel).)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK) (CHEMBL2221347) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.05 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL42205 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL42205 | — | IC50 | = | 9.0 | nM | 8.05 |