Assay Detail
Binding
CHEMBL680968
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Inhibition of peptide EPQ (pY) EEIPI binding to Fyn protein kinase SH2 domain
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Covalent binding of catechols to src family SH2 domains
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.08 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL16028 | — | — | 1 | 6.00 |
| CHEMBL416353 | — | — | 1 | 6.00 |
| CHEMBL277743 | — | — | 1 | 5.00 |
| CHEMBL416166 | — | — | 1 | 5.00 |
| CHEMBL15285 | — | — | 1 | 5.00 |
| CHEMBL277347 | — | — | 1 | 5.00 |
| CHEMBL15887 | — | — | 1 | 4.30 |
| CHEMBL274926 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL16028 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL416353 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL277743 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL416166 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL15285 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL277347 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL15887 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL274926 | — | IC50 | = | 50000.0 | nM | 4.30 |