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Assay Detail

CHEMBL681649

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of yeast Farnesyl transferase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 6 — Multiple protein complex / RNA
Curated By Expert

Target

Farnesyltransferase (CHEMBL2111393)
Type PROTEIN COMPLEX
Organism Saccharomyces cerevisiae S288c

Publication

Synthesis and evaluation of benzophenone-based photoaffinity labeling analogs of prenyl pyrophosphates containing stable amide linkages
Turek TC, Gaon I, Gamache D, Distefano MD
Bioorg Med Chem Lett (1997) 7 : 2125 -2130
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.12 7.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL69330 FARNESYL DIPHOSPHATE 1 7.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL69330 FARNESYL DIPHOSPHATE Kd = 75.0 nM 7.12