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Assay Detail

CHEMBL681696

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for its ability to displace radiolabeled glucagon
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glucagon receptor (CHEMBL4720)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Development of potent truncated glucagon antagonists.
Ahn JM, Medeiros M, Trivedi D, Hruby VJ.
J Med Chem (2001) 44 : 1372 -1379
PubMed 11311060 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.88 8.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL413890 1 8.43
CHEMBL438045 1 7.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL413890 IC50 = 3.75 nM 8.43
CHEMBL438045 IC50 = 48.0 nM 7.32