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Assay Detail

CHEMBL683426

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Concentration required to inhibit Fatty-acid amide hydrolase (FAAH) at pH 7.0
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Fatty-acid amide hydrolase 1 (CHEMBL2243)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase.
Patricelli MP, Patterson JE, Boger DL, Cravatt BF.
Bioorg Med Chem Lett (1998) 8 : 613 -618
PubMed 9871570 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.60 5.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL155928 1 5.68
CHEMBL347894 1 5.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL155928 IC50 = 2100.0 nM 5.68
CHEMBL347894 IC50 = 3100.0 nM 5.51