Assay Detail
Binding
CHEMBL683643
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Inhibition of bovine Geranylgeranyl transferase type I
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N-Arylalkyl pseudopeptide inhibitors of farnesyltransferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.31 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1790750 | — | — | 1 | 8.00 |
| CHEMBL1790748 | — | — | 1 | 6.35 |
| CHEMBL1790756 | — | — | 1 | 5.33 |
| CHEMBL1790745 | — | — | 1 | 5.24 |
| CHEMBL1790753 | — | — | 1 | 5.00 |
| CHEMBL1790752 | — | — | 1 | 5.00 |
| CHEMBL1790754 | — | — | 1 | 5.00 |
| CHEMBL1790760 | — | — | 1 | 4.41 |
| CHEMBL1790744 | — | — | 1 | 4.37 |
| CHEMBL2052018 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1790750 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL1790748 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL1790756 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL1790745 | — | IC50 | = | 5750.0 | nM | 5.24 |
| CHEMBL1790753 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1790752 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1790754 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1790760 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL1790744 | — | IC50 | = | 43000.0 | nM | 4.37 |
| CHEMBL2052018 | — | IC50 | = | 45000.0 | nM | 4.35 |