Assay Detail
Functional
CHEMBL683684
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of recombinant HIV-1 IIIB mutant Y181C
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.19 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL338435 | — | — | 1 | 6.29 |
| CHEMBL338979 | — | — | 1 | 6.18 |
| CHEMBL331912 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL338435 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL338979 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL331912 | — | IC50 | = | 790.0 | nM | 6.10 |